Article
Characterization of liver function in transdifferentiated hepatocytes.
Journal of cellular physiology - 1 Jan 2006
Burke Zoë D, Shen Chia-Ning, Ralphs Kate L, Tosh David
Abstract excerpt
We previously demonstrated that dexamethasone (Dex) induces the transdifferentiation (or conversion) of the pancreatic progenitor cell line AR42J-B13 (B13) to hepatocytes based on the expression of liver proteins. We have extended our original observations to determine: (1) the effects of Dex on pancreatic gene expression; (2) the time course of expression of liver enriched transcription factors during conversion...
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