Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver.

doi:10.1634/stemcells.2006-0664

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Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver.

Stem cells (Dayton, Ohio) - 1 Jul 2007

Duret Cédric, Gerbal-Chaloin Sabine, Ramos Jeanne, Fabre Jean-Michel, Jacquet Eric, Navarro Francis, Blanc Pierre, Sa-Cunha Antonio, Maurel Patrick, Daujat-Chavanieu Martine

Abstract excerpt

Activation and proliferation of human liver progenitor cells has been observed during acute and chronic liver diseases. Our goal was to investigate the presence of these putative progenitors in the liver of patients who underwent lobectomy for various reasons but did not show any hepatic insufficiency. Hepatic lesions were evaluated by histological analysis. Nonparenchymal epithelial (NPE) cells were isolated...

Topics

Adult
Aged
Biomarkers
Blood Proteins
Cell Differentiation
Cell Lineage
Cell Separation
Epithelial Cells
Female
Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatocyte Nuclear Factor 4

Hepatocytes

Humans

Liver

Male

Middle Aged

Phenotype

Source

Open in PubMed

Identifiers

PMID: 17412893
DOI: 10.1634/stemcells.2006-0664

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