Article
Differentiated properties of hepatocytes induced from pancreatic cells.
Hepatology (Baltimore, Md.) - 1 Sept 2002
Tosh David, Shen Chia-Ning, Slack Jonathan M W
Abstract excerpt
Transdifferentiation of pancreas to liver is a well-recognized phenomenon and has been described in animal experiments and human pathology. We recently produced an in vitro model for the transdifferentiation (or conversion) of the pancreatic cell line AR42J-B13 to hepatocytes based on culture with dexamethasone (Dex). To determine whether the hepatocytes express markers of hepatic intermediary metabolism and...
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