Article
Discovery of compounds that will prevent tau pathology.
Journal of molecular neuroscience : MN - 1 Dec 2002
Kosik Kenneth S, Ahn Jae, Stein Ross, Yeh Li-An
Abstract excerpt
Tau is certainly a reasonable target for the development of compounds to prevent neurofibrillary pathology, particularly in the fronto-temporal dementias. Although the mechanism of the filamentous accumulations remains unclear, sufficient knowledge is in place to move forward with high throughput screens. In fact, the development of compounds from such screens will ultimately be the only way to validate the...
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