Article
Changes of sphingolipid species in the phenotype conversion from myofibroblasts to lipocytes in hepatic stellate cells.
Journal of cellular biochemistry - 15 Feb 2003
Andrade Claudia M B, Trindade Vera M T, Cardoso Carla C A, Ziulkoski Ana L, Trugo Luiz C, Guaragna Regina M, Borojevic Radovan, Guma Fátima C R
Abstract excerpt
Sphingolipids play a relevant role in cell-cell interaction, communication, and migration. We studied the sphingolipid content in the murine hepatic stellate cell line GRX, which expresses the myofibroblast phenotype, and can be induced in vitro to display the fat-storing phenotype. Lipid modifications along this induction were investigated by labeling sphingolipids with [(14)C]galactose, [(14)C]serine, or...
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