Article
Intermediate filaments modulation in an in vitro model of the hepatic stellate cell activation or conversion into the lipocyte phenotype.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 2001
Guma FCR, Mello T G, Mermelstein C S, Fortuna V A, Wofchuk S T, Gottfried C, Guaragna R M, Costa M L, Borojevic R
Abstract excerpt
Hepatic stellate cells are intralobular connective tissue cells expressing the myofibroblast or the lipocyte phenotypes. They participate in homeostasis of the liver extracellular matrix, repair, regeneration, and fibrosis under the former phenotype, and control the retinol metabolism, storage, and release under the latter one. They are heterogeneous in terms of their tissue distribution, function, and expression...
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