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Article

Phospholipid modifications during conversion of hepatic myofibroblasts into lipocytes (Ito-cells).

Biochimica et biophysica acta - 30 Oct 1992

Guaragna R M, Trugo L, Borojevic R

Abstract excerpt

Connective tissue cells of liver parenchyma (perisinusoidal myofibroblasts) can be induced to express the lipocyte (Ito cell) phenotype. We have studied phospholipid synthesis and phosphate incorporation during this in vitro conversion, induced by insulin and/or indomethacin, in the established murine cell line GRX. Phospholipid synthesis, measured by [14C]acetate incorporation, was increased after a full...

Topics

Acetates
Adipose Tissue
Cell Line
Fatty Acids, Unsaturated
Fibroblasts
Indomethacin
Insulin
Liver
Phenotype
Phosphates
Phosphatidic Acids
Phosphatidylinositols

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Phospholipids

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Identifiers

PMID: 1420296
DOI: 10.1016/0005-2760(92)90313-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1420296-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Phospholipid modifications during conversion of hepatic myofibroblasts into lipocytes (Ito-cells).PMID 1420296Read ↗

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