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Article

Neutral lipid synthesis and accumulation during in vitro induction of the lipocyte phenotype in hepatic connective tissue cells.

Biochimica et biophysica acta - 20 Aug 1991

Guaragna R M, Trugo L, Borojevic R

Abstract excerpt

Connective tissue cells of liver parenchyma are known as hepatic myofibroblasts and lipocytes (fat-storing cells, Ito-cells). They are considered to belong to a single cell lineage, that may switch between these two phenotypes. We have studied cellular and molecular parameters and controls of this switch in the murine GRX cell line, established from liver fibro-granulomatous lesions induced by schistosomal...

Topics

Animals
Cell Differentiation
Cell Line
Chromatography, Gas
Chromatography, Thin Layer
Connective Tissue
Connective Tissue Cells
Fatty Acids
Indomethacin
Insulin
Lipid Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipids

Liver

Mice

Phenotype

Schistosomiasis

Source

Identifiers

PMID: 1892875
DOI: 10.1016/0005-2760(91)90228-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1892875-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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