Article
In vitro induction of the fat-storing phenotype in a liver connective tissue cell line-GRX.
In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 Apr 1990
Borojevic R, Guaragna R M, Margis R, Dutra H S
Abstract excerpt
Liver connective tissue cells have been characterized as perisinusoidal myofibroblasts and hepatic lipocytes (Ito cells, fat-storing cells). A concept of a single mesenchymal cell population that may be modulated between these two phenotypes has been postulated. We have previously established a continuous murine cell line, GRX, obtained from fibrotic granulomatous lesions induced by schistosomal infection in...
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