Article
Retinol uptake and metabolism, and cellular retinol binding protein expression in an in vitro model of hepatic stellate cells.
Molecular and cellular biochemistry - 1 Oct 1998
Vicente C P, Fortuna V A, Margis R, Trugo L, Borojevic R
Abstract excerpt
Liver is a major site of retinoid metabolism and storage, and more than 80% of the liver retinoids are stored in hepatic stellate cells. These cells represent less than 1% of the total liver protein, reaching a very high relative intracellular retinoid concentration. The plasma level of retinol i...
Topics
- Adipocytes
- Animals
- Binding Sites
- Cell Differentiation
- Cell Line
- Cell Size
- Centrifugation, Density Gradient
- Cytosol
- Fibroblasts
- Gene Expression
- Indomethacin
- Liver
- Mice
- Phenotype
- Retinol-Binding Proteins
- Retinol-Binding Proteins, Cellular
- Retinol-Binding Proteins, Plasma
- Reverse Transcriptase Polymerase Chain Reaction