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Article

Variations of ganglioside biosynthetic pathways in the phenotype conversion from myofibroblasts to lipocytes in murine hepatic stellate cell line.

Molecular and cellular biochemistry - 1 Sept 2007

de Aguirres Aline B, Mello Paola A, Andrade Claudia M B, Breier Ana Carolina, Margis Rogério, Guaragna Regina M, Borojevic Radovan, Guma Fátima C R, Trindade Vera M T

Abstract excerpt

GRX cell line represents hepatic stellate cell and can be transformed from an actively proliferation myofibroblast phenotype into a quiescent fat-storing lipocyte phenotype. Both express the same gangliosides (GM3, GM2, GM1 and GD1a), which are resolved as doublets on HPTLC. Upper/lower band ratio is increased in lipocyte-like cells and the upper band is composed by ceramides with long-chain fatty acids. This...

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PMID: 17440688
DOI: 10.1007/s11010-007-9464-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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