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Article

A nuclear 3'-5' exonuclease proofreads for the exonuclease-deficient DNA polymerase alpha.

DNA repair - 1 Oct 2002

Brown Kevin R, Weatherdon Krista L, Galligan Carole L, Skalski Violetta

Abstract excerpt

DNA replication is a highly accurate process designed to duplicate the entire genome of a cell during each cell division. The accuracy of DNA replication is derived from the balance between three important components: base selectivity by the replicative DNA polymerases (pols), exonucleolytic proofreading, and post-replicative mismatch repair. Previously we identified a human 3'-5' exonuclease (exoN) whose...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12531027
DOI: 10.1016/s1568-7864(02)00115-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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