Article
Fidelity of DNA replication-a matter of proofreading.
Current genetics - 1 Oct 2018
Bębenek Anna, Ziuzia-Graczyk Izabela
Abstract excerpt
DNA that is transmitted to daughter cells must be accurately duplicated to maintain genetic integrity and to promote genetic continuity. A major function of replicative DNA polymerases is to replicate DNA with the very high accuracy. The fidelity of DNA replication relies on nucleotide selectivity of replicative DNA polymerase, exonucleolytic proofreading, and postreplicative DNA mismatch repair (MMR)....
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