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Article

Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae.

DNA repair - 3 Nov 2002

Tran Phuoc T, Erdeniz Naz, Dudley Sandra, Liskay R Michael

Abstract excerpt

Exo1p is a member of the Rad2p family of structure-specific nucleases that contain conserved N and I nuclease domains. Exo1p has been implicated in numerous DNA metabolic processes, such as recombination, double-strand break repair and DNA mismatch repair (MMR). In this report, we describe in vitro and in vivo characterization of full-length wild-type and mutant forms of Exo1p. Herein, we demonstrate that...

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Identifiers

PMID: 12531018
DOI: 10.1016/s1568-7864(02)00114-3

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