Article
Exonuclease 1-dependent and independent mismatch repair.
DNA repair - 1 Aug 2015
Goellner Eva M, Putnam Christopher D, Kolodner Richard D
Abstract excerpt
DNA mismatch repair (MMR) acts to repair mispaired bases resulting from misincorporation errors during DNA replication and also recognizes mispaired bases in recombination (HR) intermediates. Exonuclease 1 (Exo1) is a 5' → 3' exonuclease that participates in a number of DNA repair pathways. Exo1 was identified as an exonuclease that participates in Saccharomyces cerevisiae and human MMR where it functions to...
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