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Article

DNA gyrase requirements distinguish the alternate pathways of Mu transposition.

Molecular microbiology - 1 Jan 2003

Sokolsky Tanya D, Baker Tania A

Abstract excerpt

The MuA transposase mediates transposition of bacteriophage Mu through two distinct mechanisms. The first integration event following infection occurs through a non-replicative mechanism. In contrast, during lytic growth, multiple rounds of replicative transposition amplify the phage genome. We have examined the influence of gyrase and DNA supercoiling on these two transposition pathways using both a...

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Identifiers

PMID: 12519191
DOI: 10.1046/j.1365-2958.2003.03296.x

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