Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence and positional requirements for DNA sites in a mu transpososome.

The Journal of biological chemistry - 8 Mar 2002

Goldhaber-Gordon Ilana, Early Michael H, Gray Matthew K, Baker Tania A

Abstract excerpt

Transposition of bacteriophage Mu uses two DNA cleavage sites and six transposase recognition sites, with each recognition site divided into two half-sites. The recognition sites can activate transposition of non-Mu DNA sequences if a complete set of Mu sequences is not available. We have analyzed 18 sequences from a non-Mu DNA molecule, selected in a functional assay for the ability to be transposed by MuA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophage phi X 174
Share to Binding Sites
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Models, Biological

Share to Protein Structure, Tertiary

Share to Sequence Homology, Nucleic Acid

Share to Transposases

Source

Identifiers

PMID: 11756424
DOI: 10.1074/jbc.M110342200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence and positional requirements for DNA sites in a mu transpososome.PMID 11756424Read ↗

MuA transposase separates DNA sequence recognition from catalysis.Semantic proximity Read ↗

Progressive structural transitions within Mu transpositional complexes.Semantic proximity Read ↗

Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering.Semantic proximity Read ↗

Complete transposition requires four active monomers in the mu transposase tetramer.Semantic proximity Read ↗

The emerging diversity of transpososome architectures.Semantic proximity Read ↗

Step-arrest mutants of phage Mu transposase. Implications in DNA-protein assembly, Mu end cleavage, and strand transfer.Semantic proximity Read ↗

Crosstalk between transposase subunits during cleavage of the mariner transposon.Semantic proximity Read ↗

The conserved CA/TG motif at Mu termini: T specifies stable transpososome assembly.Semantic proximity Read ↗

Importance of the conserved CA dinucleotide at Mu termini.Semantic proximity Read ↗

A DNA gyrase-binding site at the center of the bacteriophage Mu genome is required for efficient replicative transposition.Semantic proximity Read ↗

Effect of mutations in the Mu-host junction region on transpososome assembly.Semantic proximity Read ↗

Stimulation of the Mu A protein-mediated strand cleavage reaction by the Mu B protein, and the requirement of DNA nicking for stable type 1 transpososome formation. In vitro transposition characteristics of mini-Mu plasmids carrying terminal base pair mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.