Article
A DNA gyrase-binding site at the center of the bacteriophage Mu genome is required for efficient replicative transposition.
Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 1990
Pato M L, Howe M M, Higgins N P
Abstract excerpt
We have discovered a centrally located site that is required for efficient replication of bacteriophage Mu DNA and identified it as a strong DNA gyrase-binding site. Incubation of Mu DNA with gyrase and enoxacin revealed a cleavage site 18.1 kilobases from the left end of the 37.2-kilobase genome...
Topics
- Bacteriophage mu
- Base Sequence
- Binding Sites
- DNA Replication
- DNA Topoisomerases, Type II
- DNA Transposable Elements
- DNA, Superhelical
- DNA, Viral
- Molecular Sequence Data
- Mutation
- Restriction Mapping