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Article

DNA recognition and the precleavage state during single-stranded DNA transposition in D. radiodurans.

The EMBO journal - 17 Nov 2010

Hickman Alison Burgess, James Jeffrey A, Barabas Orsolya, Pasternak Cécile, Ton-Hoang Bao, Chandler Michael, Sommer Suzanne, Dyda Fred

Abstract excerpt

Bacterial insertion sequences (ISs) from the IS200/IS605 family encode the smallest known DNA transposases and mobilize through single-stranded DNA transposition. Transposition by one particular family member, ISDra2 from Deinococcus radiodurans, is dramatically stimulated upon massive γ irradiation. We have determined the crystal structures of four ISDra2 transposase/IS end complexes; combined with in vivo...

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Identifiers

PMID: 20890269
DOI: 10.1038/emboj.2010.241
PMCID: PMC2989099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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