Article
Importance of the conserved CA dinucleotide at Mu termini.
Journal of molecular biology - 30 Nov 2001
Lee I, Harshey R M
Abstract excerpt
The dinucleotide CA found at the termini of transposable phage Mu also occurs at the termini of a large class of transposable elements, including HIV, all retroviruses and many retrotransposons. In order to understand the importance of this sequence conservation, the activity of all 16 dinucleotide permutations of the termini was first examined using a sensitive plasmid-based in vivo transposition assay. The...
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