Article
Mu insertions are repaired by the double-strand break repair pathway of Escherichia coli.
PLoS genetics - 1 Jan 2012
Jang Sooin, Sandler Steven J, Harshey Rasika M
Abstract excerpt
Mu is both a transposable element and a temperate bacteriophage. During lytic growth, it amplifies its genome by replicative transposition. During infection, it integrates into the Escherichia coli chromosome through a mechanism not requiring extensive DNA replication. In the latter pathway, the transposition intermediate is repaired by transposase-mediated resecting of the 5' flaps attached to the ends of the...
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