Article
Analysis of expressed V(H) genes in persistent polyclonal B cell lymphocytosis reveals absence of selection in CD27+IgM+IgD+ memory B cells.
European journal of immunology - 1 Dec 2002
Loembé Marguerite Massinga, Néron Sonia, Delage Robert, Darveau André
Abstract excerpt
Persistent polyclonal B cell lymphocytosis (PPBL) is a hematological disorder diagnosed predominantly in women, characterized by a polyclonal increase in the number of peripheral blood B lymphocytes. Abnormality of the B cell population was evidenced by the finding of multiple bcl-2/Ig gene rearrangements and an additional long-arm chromosome within a significant proportion of B cells. To gain further insight...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
