Article
Limited evolution of HIV antiretroviral drug resistance-associated mutations during the performance of drug resistance testing.
Journal of acquired immune deficiency syndromes (1999) - 1 Jan 2003
Birch Chris, Middleton Tracey, Hales Gillian, Cooper David, Law Matthew, Crowe Suzanne, Hoy Jennifer, Emery Sean
Abstract excerpt
We investigated the evolution of HIV reverse transcriptase (RT)- and protease-associated antiretroviral (ARV) drug resistance mutations during the time taken to perform genotypic drug resistance testing. Thirty treatment-experienced patients who were adherent to therapy and who underwent genotypic drug resistance testing provided blood samples at randomization and when reviewing the test results (baseline)....
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