Article
HIV-1 drug resistance evolution among patients on potent combination antiretroviral therapy with detectable viremia.
Journal of acquired immune deficiency syndromes (1999) - 1 Sept 2005
Napravnik Sonia, Edwards David, Stewart Paul, Stalzer Brant, Matteson Elizabeth, Eron Joseph J
Abstract excerpt
Many patients infected with HIV do not achieve or maintain virologic suppression below levels of detection while on potent combination antiretroviral therapy. The likelihood of emergence of incident mutations conferring reduced antiretroviral drug susceptibility was estimated among patients maintained on a stable regimen with ongoing detectable plasma HIV RNA levels. Ninety-eight HIV-infected patients were...
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