Article
Application of HIV-1 genotypic-resistance testing prevents the evolution of further resistance mutations in heavily pretreated patients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2001
Zöllner B, Feucht H H, Weitner L, Adam A, Schröter M, Schäfer P, Laufs R
Abstract excerpt
BACKGROUND: Resistance-associated mutations in HIV-1 evolve even under highly active antiretroviral therapy. OBJECTIVE: To evaluate the clinical efficacy of genotypic-resistance testing (GRT), to estimate the potential of a given antiretroviral therapy for prevention of further resistance mutations. STUDY DESIGN: Ten patients were treated prospectively with drugs, according to the results of a GRT. Five patients...
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