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Article

Progressive reversion of human immunodeficiency virus type 1 resistance mutations in vivo after transmission of a multiply drug-resistant virus.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Dec 2003

Gandhi Rajesh T, Wurcel Alysse, Rosenberg Eric S, Johnston Mary N, Hellmann Nicholas, Bates Michael, Hirsch Martin S, Walker Bruce D

Abstract excerpt

Evolution and transmission of multiply drug-resistant human immunodeficiency virus type 1 (HIV-1) may limit therapeutic options as global treatment efforts expand. However, the stability of these mutants in the absence of drug selection pressure is not known. We performed a longitudinal analysis of plasma virus from a person who acquired HIV-1 that contained multiple reverse transcriptase (RT) and protease (PR)...

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Identifiers

PMID: 14689353
DOI: 10.1086/379773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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