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Article

Interleukin-1beta gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection.

Hepatology (Baltimore, Md.) - 1 Jan 2003

Wang Yue, Kato Naoya, Hoshida Yujin, Yoshida Hideo, Taniguchi Hiroyoshi, Goto Tadashi, Moriyama Masaru, Otsuka Motoyuki, Shiina Shuichiro, Shiratori Yasushi, Ito Yoichi, Omata Masao

Abstract excerpt

Hepatitis C virus (HCV) infection is a major risk factor for developing hepatocellular carcinoma (HCC), a life-threatening sequel. However, the factors that affect disease progression to HCC have not been thoroughly elucidated. Genetic polymorphisms in proinflammatory cytokines, the interleukin 1 (IL-1) family (IL-1beta and IL-1ra) and tumor necrosis factor-alpha (TNF-alpha), were studied in 274 Japanese patients...

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PMID: 12500190
DOI: 10.1053/jhep.2003.50017

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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