Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms of interleukin-1beta in association with the development of alcoholic liver disease in Japanese patients.

The American journal of gastroenterology - 1 May 2000

Takamatsu M, Yamauchi M, Maezawa Y, Saito S, Maeyama S, Uchikoshi T

Abstract excerpt

OBJECTIVE: Cytokine interleukin-1beta plays a central role in the inflammation process. Serum levels of IL-1beta are elevated in patients with alcoholic liver disease (ALD), especially in those with cirrhosis and alcoholic hepatitis. Recently, the presence of genetic polymorphisms of this cytokine was confirmed. The aim of this study was to determine whether IL-1beta polymorphisms are associated with the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-1

Share to Liver Diseases, Alcoholic

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 10811344
DOI: 10.1111/j.1572-0241.2000.02030.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms of interleukin-1beta in association with the development of alcoholic liver disease in Japanese patients.PMID 10811344Read ↗

Interleukin-1beta gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection.Semantic proximity Read ↗

Interleukin-1 gene cluster polymorphisms and alcoholism in Spanish men.Semantic proximity Read ↗

Association Between Polymorphisms of Interleukin 1 Family Genes and Hepatocellular Carcinoma.Semantic proximity Read ↗

Impact of interleukin-1beta genetic polymorphisms on the development of hepatitis C virus-related hepatocellular carcinoma in Japan.Semantic proximity Read ↗

Influence of polymorphisms in TNF-α and IL1β on susceptibility to alcohol induced liver diseases and therapeutic potential of miR-124-3p impeding TNF-α/IL1β mediated multi-cellular signaling in liver microenvironment.Semantic proximity Read ↗

Genetic variants of TNFα, IL10, IL1β, CTLA4 and TGFβ1 modulate the indices of alcohol-induced liver injury in East Indian population.Semantic proximity Read ↗

Interleukin-1beta gene polymorphism associated with hepatocellular carcinoma in hepatitis B virus infection.Semantic proximity Read ↗

Interleukin 10 promoter haplotype is associated with alcoholic liver cirrhosis in Taiwanese patients.Semantic proximity Read ↗

Genetic variants in IL33 and IL1RL1 genes confer susceptibility to HBV-related liver cirrhosis in Chinese Han population.Semantic proximity Read ↗

Cytokine gene polymorphisms in heavy drinkers with and without decompensated liver disease: a case-control study.Semantic proximity Read ↗

Interleukin-10 gene promoter polymorphism and susceptibility to liver cirrhosis.Semantic proximity Read ↗

Polymorphisms in the IL-1 gene cluster influence systemic inflammation in patients at risk for acute-on-chronic liver failure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.