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Article

Impact of cytokine gene variants on the prediction and prognosis of hepatocellular carcinoma in patients with cirrhosis.

Journal of hepatology - 1 Aug 2014

Tarhuni Arige, Guyot Erwan, Rufat Pierre, Sutton Angela, Bourcier Valérie, Grando Véronique, Ganne-Carrié Nathalie, Ziol Marianne, Charnaux Nathalie, Beaugrand Michel, Moreau Richard, Trinchet Jean-Claude, Mansouri Abdellah, Nahon Pierre

Abstract excerpt

BACKGROUND & AIMS: Genetic polymorphisms modulate the expression of proinflammatory cytokines. We prospectively assessed the influence of 6 single nucleotide polymorphisms (SNPs) in TNFα, IL6, and IL1β genes on the risk of hepatocellular carcinoma (HCC) in patients with cirrhosis. METHODS: TNFα (G-238A, C-863A, G-308A), IL6 (C-174G), and IL1β (C-31T, C-511T) SNPs were assessed in 232 alcoholics and 253...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24751829
DOI: 10.1016/j.jhep.2014.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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