Article
Impact of interleukin IL-6 rs-1474347 and IL-10 rs-1800896 genetic polymorphisms on the susceptibility of HCV-infected Egyptian patients to hepatocellular carcinoma.
Immunologic research - 1 Jun 2020
Abd El-Baky Reham M, Hetta Helal F, Koneru Gopala, Ammar Marwa, Shafik Engy A, Mohareb Dina A, Abbas El-Masry Muhammad, Ramadan Haidi K, Abu Rahma Mohamed Zakaria, Fawzy Michael A, Fathy Moustafa
Abstract excerpt
Hepatitis C virus (HCV) is considered leading cause of cirrhosis and hepatocellular carcinoma (HCC). We aimed to examine the association of IL-6 and IL-10 single-nucleotide polymorphisms with the progression of chronic HCV (CHC) infection to cirrhosis and HCC. For comparative purposes, four groups were enrolled; chronic HCV group (CHC, n = 22), HCV-related liver cirrhosis group (HCV-LC, n = 22), HCV-related HCC...
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