Article
Interleukin-1beta gene polymorphism associated with hepatocellular carcinoma in hepatitis B virus infection.
World journal of gastroenterology - 7 Feb 2006
Hirankarn Nattiya, Kimkong Ingorn, Kummee Pittaya, Tangkijvanich Pisit, Poovorawan Yong
Abstract excerpt
AIM: To examine the effect of interleukin-1-beta (IL-1beta) promoter region C-511T and IL-1 receptor antagonist (IL-1RN) polymorphism among the patients with chronic hepatitis B virus (HBV) infection (HCC and non-HCC). METHODS: Genomic DNA from 136 Thai patients with chronic HBV infection (HCC=46 and non-HCC=90) and 152 healthy individuals was genotyped for IL-1beta gene polymorphism (-511) using polymerase chain...
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