Article
Association Between Polymorphisms of Interleukin 1 Family Genes and Hepatocellular Carcinoma.
Medical science monitor : international medical journal of experimental and clinical research - 26 May 2018
Tak Ki Hong, Yu Gyeong Im, Lee Mi Young, Shin Dong Hoon
Abstract excerpt
BACKGROUND Hepatocellular carcinoma (HCC) is one of the most common malignancies occurring worldwide and is most frequent type of liver cancer. The risk for developing HCC increases with the severity of inflammation and fibrosis. The members of the interleukin-1 (IL-1) family are primarily proinflammatory cytokines due to their ability to stimulate the expression of genes associated with inflammation and...
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