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Article

Tumor necrosis factor-alpha -308G/A polymorphism and risk of hepatocellular carcinoma in hepatitis C virus-infected patients.

Chinese journal of cancer - 1 Jan 2012

Talaat Roba M, Esmail Ahmed A, Elwakil Reda, Gurgis Adel A, Nasr Mahmoud I

Abstract excerpt

Tumor necrosis factor-alpha (TNF-α) is an important cytokine in generating an immune response against infection with hepatitis C virus (HCV). The functions of TNF-α may be altered by single-nucleotide polymorphisms (SNPs) in its gene structure. We hypothesized that SNPs in TNF-α may be important in determining the outcome of an HCV infection. To test this hypothesis, we investigated the role of the polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22200181
DOI: 10.5732/cjc.011.10258
PMCID: PMC3777466

Genes

TNF

Provenance

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