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Article

Extensive allelic sequence variation in the J region of the human immunoglobulin heavy chain gene locus.

European journal of immunology - 1 Sept 1995

Mattila P S, Schugk J, Wu H, Mäkelä O

Abstract excerpt

During the initial stages of B lymphocyte differentiation heavy chain variable (VH), diversity (DH) and joining (JH) gene segments recombine to form a functional heavy chain variable region (VDJ) gene. Evidence for genetic polymorphism of the human JH gene segments has been obtained from mature rearranged VDJ sequences. We conducted an analysis of the published rearranged JH gene sequences and found that the JH...

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Source

Identifiers

PMID: 7589129
DOI: 10.1002/eji.1830250926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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