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Effective strategy of dendritic cell-based immunotherapy for advanced tumor-bearing hosts: the critical role of Th1-dominant immunity.

Molecular cancer therapeutics - 1 Aug 2002

Mashino Kohjiro, Sadanaga Noriaki, Tanaka Fumiaki, Ohta Mitsuhiko, Yamaguchi Hiroshi, Mori Masaki

Abstract excerpt

Although dendritic cell (DC)-based cancer-specific immunotherapy is a potent strategy for various types of carcinomas, few clinical studies have yielded optimal antitumor effects. Systemic immunodeficiency is observed in patients with advanced malignant disease. In this study, we explored the ability to induce antitumor immunity of the cultured monocyte-derived DCs from hosts with advanced malignant disease,...

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PMID: 12492111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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