Article

Glycyrrhiza uralensis polysaccharides as a Dendritic Cell-Based Vaccine Adjuvant: Enhanced Cancer Immunotherapy Combined with PD-1 Blockade

2025-04-21

Abstract excerpt

The activation of naive CD8+T cells by mature dendritic cells (DCs) through antigen presentation is essential for initiating effective anti-tumor immunity. In our previous study, Glycyrrhiza uralensis polysaccharides (GUPS) were prepared and found that they significantly promoted the maturation and cytokine secretion of human Mo-DC and murine BM-DC through TLR4 signaling pathways. In this study, HPV-DC vaccine pre...

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Literature Corpus work: b87b3229-b7a8-510a-8005-fd98b10ecb81
DOI: 10.22541/au.174523381.19231939/v1

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