Article
Protective antitumor activity through dendritic cell immunization is mediated by NK cell as well as CTL activation.
Archives of pharmacal research - 1 Aug 1999
Kim K D, Kim J K, Kim S J, Choe I S, Chung T H, Choe Y K, Lim J S
Abstract excerpt
Dendritic cells (DCs) are potent professional antigen-presenting cells (APC) capable of inducing the primary T cell response to antigen. Although tumor cells express target antigens, they are incapable of stimulating a tumor-specific immune response due to a defect in the costimulatory signal tha...
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