Tumor-associated human dendritic cell subsets: Phenotype, functional orientation, and clinical relevance.

Abstract excerpt

DCs play a pivotal role in orchestrating innate and adaptive antitumor immunity. Activated DCs can produce large amounts of various proinflammatory cytokines, initiate T-cell responses, and exhibit direct cytotoxicity against tumor cells. They also efficiently enhance the antitumoral properties of NK cells and T lymphocytes. Based on these capabilities, immunogenic DCs promote tumor elimination and are associated...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cytokines
• Share to Dendritic Cells