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Article

Dendritic cell vaccination with a toll-like receptor agonist derived from mycobacteria enhances anti-tumor immunity.

Oncotarget - 20 Oct 2015

Vo Manh-Cuong, Lee Hyun-Ju, Kim Jong-Seok, Hoang My-Dung, Choi Nu-Ri, Rhee Joon Haeng, Lakshmanan Vinoth-Kumar, Shin Sung-Jae, Lee Je-Jung

Abstract excerpt

Dendritic cell (DC)-based vaccines are considered useful in cancer immunotherapy, and the interaction of DC and adjuvants is important in the design of the next generation vaccines. In this study, whether DC combined with Rv2299c derived from mycobacteria could improve anti-tumor immune responses in a colon cancer mouse model was evaluated. MC38 cell lines were injected subcutaneously to establish...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26418952
DOI: 10.18632/oncotarget.5281
PMCID: PMC4741802

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