Article
[High-resolution analysis of chromosome 5 and identification of candidate genes in gastric cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Feb 2006
Yu Ying-yan, Ji Jun, Lu Yun, Bu Lei, Liu Bing-ya, Zhu Zheng-gang, Lin Yan-zhen
Abstract excerpt
OBJECTIVE: To explore the relationship between loss of heterozygosity (LOH) of 5p with the histological phenotype in gastric cancer. METHODS: Eighty pairs of tumor and adjacent normal mucosa samples were collected and genomic DNA was extracted. Total of 17 polymorphic microsatellite markers for 5p were used for LOH analysis. A part of samples were fixed in 10% buffered formalin and stained with H&E. Histological...
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