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Article

Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumors.

International journal of cancer - 10 Feb 2002

Csiszar Katalin, Fong Sheri F T, Ujfalusi Aniko, Krawetz Stephen A, Salvati Eugene P, Mackenzie James W, Boyd Charles D

Abstract excerpt

Lysyl oxidase (LOX), a copper-dependent amine oxidase, has been implicated in tumor suppression and cell growth regulation. The chromosomal locus of LOX, 5q23, is affected by loss of heterozygosity (LOH) in colon cancer, suggesting that the LOX gene could be affected by LOH and consequently, loss or reduction of LOX function contribute to the tumorigenic process. Identification of microsatellite markers within...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11807790
DOI: 10.1002/ijc.10035

Genes

LOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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