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Article

Modulation of homomeric and heteromeric KCNQ1 channels by external acidification.

The Journal of physiology - 15 Dec 2002

Peretz Asher, Schottelndreier Hella, Aharon-Shamgar Liora Ben, Attali Bernard

Abstract excerpt

The I(KS) K(+) channel plays a major role in repolarizing the cardiac action potential. It consists of an assembly of two structurally distinct alpha and beta subunits called KCNQ1 and KCNE1, respectively. Using two different expression systems, Xenopus oocytes and Chinese hamster ovary cells, we investigated the effects of external protons on homomeric and heteromeric KCNQ1 channels. External acidification (from...

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Identifiers

PMID: 12482884
DOI: 10.1113/jphysiol.2002.028381
PMCID: PMC2290713

Genes

KCNQ1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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