Article
Role of microglial cells in selective replication of simian immunodeficiency virus genotypes in the brain.
Journal of virology - 1 Jan 2003
Babas Tahar, Muñoz Daniel, Mankowski Joseph L, Tarwater Patrick M, Clements Janice E, Zink M Christine
Abstract excerpt
An accelerated, consistent macaque simian immunodeficiency virus (SIV) model in which over 90% of pigtailed macaques (Macaca nemestrina) coinoculated with SIV/17E-Fr and SIV/DeltaB670 developed encephalitis was used to determine whether central nervous system (CNS) lesions are associated with the replication of specific genotypes in the brain and, more specifically, in the microglia. Ten of 11 inoculated macaques...
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