Article
In vitro and in vivo infection of rhesus monkey microglial cells by simian immunodeficiency virus.
Virology - 1 Aug 1993
Brinkmann R, Schwinn A, Müller J, Stahl-Hennig C, Coulibaly C, Hunsmann G, Czub S, Rethwilm A, Dörries R, ter Meulen V
Abstract excerpt
The observation that microglial cells in brain tissue are probably a major target for human immunodeficiency virus (HIV) infection has raised interest in the pathogenic role of this cell population for the development of neuro-AIDS. Since it is very difficult to obtain microglia from normal or diseased human brain we studied microglial cells isolated from fresh brain tissue of uninfected and simian...
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