Article
Pathogenesis of SIV pneumonia: selective replication of viral genotypes in the lung.
Virology - 1 Sept 2001
Babas T, Vieler E, Hauer D A, Adams R J, Tarwater P M, Fox K, Clements J E, Zink M C
Abstract excerpt
Lymphocytic interstitial pneumonia of HIV-infected individuals and SIV pneumonia of macaques are both characterized by diffuse infiltration of the lungs with lymphocytes, plasma cells, and macrophages. This study was undertaken to determine whether there are specific, macrophage-tropic genotypes that selectively replicate in the lung of macaques with SIV pneumonia, as in SIV encephalitis. Using a rapid,...
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