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Analysis of simian immunodeficiency virus sequence variation in tissues of rhesus macaques with simian AIDS

1 Nov 1993

Abstract excerpt

One rhesus macaque displayed severe encephalomyelitis and another displayed severe enterocolitis following infection with molecularly cloned simian immunodeficiency virus (SIV) strain SIVmac239. Little or no free anti-SIV antibody developed in these two macaques, and they died relatively quickly (4 to 6 months) after infection. Manifestation of the tissue-specific disease in these macaques was associated with the...

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PMID: 8411355
DOI: 10.1128/jvi.67.11.6522-6534.1993

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