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Article

Deletion of individual mRNA capping genes is unexpectedly not lethal to Candida albicans and results in modified mRNA cap structures.

Eukaryotic cell - 1 Dec 2002

Dunyak Donna S, Everdeen Daniel S, Albanese Joseph G, Quinn Cheryl L

Abstract excerpt

Eukaryotic mRNAs are modified at the 5' end with a cap structure. In fungal cells, the formation of the mRNA cap structure is catalyzed by three enzymes: triphosphatase, guanylyltransferase, and methyltransferase. Fungal capping enzymes have been proposed to be good antifungal targets because they differ significantly from their human counterparts and the genes encoding these enzymes are essential in...

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Identifiers

PMID: 12477801
DOI: 10.1128/EC.1.6.1010-1020.2002
PMCID: PMC138750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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