Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conditional mutants of the yeast mRNA capping enzyme show that the cap enhances, but is not required for, mRNA splicing.

RNA (New York, N.Y.) - 1 Jun 1996

Fresco L D, Buratowski S

Abstract excerpt

The 5' end of eukaryotic mRNAs are modified by the addition of a 7-methyl guanosine (m7G) cap. The role of the cap in translation has been well established. Additionally, studies conducted in vitro or in microinjected Xenopus oocytes have implicated the cap in RNA processing and transport. To determine the fate of uncapped mRNA in intact yeast cells, conditional alleles of the gene encoding the capping enzyme...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Molecular Sequence Data

Share to Mutation

Share to RNA, Messenger

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 8718687
PMCID: PMC1369397

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conditional mutants of the yeast mRNA capping enzyme show that the cap enhances, but is not required for, mRNA splicing.PMID 8718687Read ↗

Conditional inactivation of mRNA capping enzyme affects yeast pre-mRNA splicing in vivo.Semantic proximity Read ↗

Accelerated mRNA decay in conditional mutants of yeast mRNA capping enzyme.Semantic proximity Read ↗

Deletion of individual mRNA capping genes is unexpectedly not lethal to Candida albicans and results in modified mRNA cap structures.Semantic proximity Read ↗

mRNA capping enzyme requirement for Caenorhabditis elegans viability.Semantic proximity Read ↗

mRNA capping enzyme activity is coupled to an early transcription elongation.Semantic proximity Read ↗

Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II.Semantic proximity Read ↗

Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase.Semantic proximity Read ↗

A conserved domain of yeast RNA triphosphatase flanking the catalytic core regulates self-association and interaction with the guanylyltransferase component of the mRNA capping apparatus.Semantic proximity Read ↗

The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast.Semantic proximity Read ↗

Isolation of temperature-sensitive mutants for mRNA capping enzyme in Saccharomyces cerevisiae.Semantic proximity Read ↗

Capped mRNA degradation intermediates accumulate in the yeast spb8-2 mutant.Semantic proximity Read ↗

Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.