Article
A conserved domain of yeast RNA triphosphatase flanking the catalytic core regulates self-association and interaction with the guanylyltransferase component of the mRNA capping apparatus.
The Journal of biological chemistry - 6 Aug 1999
Lehman K, Schwer B, Ho C K, Rouzankina I, Shuman S
Abstract excerpt
The 549-amino acid yeast RNA triphosphatase Cet1p catalyzes the first step in mRNA cap formation. Cet1p consists of three domains as follows: (i) a 230-amino acid N-terminal segment that is dispensable for catalysis in vitro and for Cet1p function in vivo; (ii) a protease-sensitive segment from r...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.