Article
Allelic inactivation of the pseudoautosomal gene SYBL1 is controlled by epigenetic mechanisms common to the X and Y chromosomes.
Human molecular genetics - 1 Dec 2002
Matarazzo Maria Rosaria, De Bonis Maria Luigia, Gregory Richard I, Vacca Marcella, Hansen R Scott, Mercadante Grazia, D'Urso Michele, Feil Robert, D'Esposito Maurizio
Abstract excerpt
On the human long-arm pseudoautosomal region (XqPAR), genes that are subject to inactivation are closely linked with those that escape. Genes subject to inactivation are not only silenced on the inactive X in females, but they are also inactivated on the Y chromosome in males. One of the genes subject to this unusual inactivation pattern is the synaptobrevin-like 1 gene (SYBL1). Previously we showed that its...
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